# HRD prediction on TCGA-LUAD

Source: [HRD prediction on TCGA-LUAD](<https://www.sota2.com/research/sota/hrd-prediction-on-tcga-luad>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2026-02-26T05:24:39.912Z

Evaluation of models for predicting Homologous Recombination Deficiency (HRD) status using the Lung Adenocarcinoma (LUAD) cohort from The Cancer Genome Atlas (TCGA).

A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage.

| Scope | Recorded value |
| --- | --- |
| Task | HRD prediction |
| Dataset (including any stated split) | TCGA-LUAD |
| Metric | AUC |
| Unit | SCALAR |
| Direction | Higher is better |
| Results loaded | 18 of 18 |
| Coverage | All results currently returned for this benchmark |

Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol.

## Metrics

- [AUC](<https://www.sota2.com/research/sota/hrd-prediction-on-tcga-luad.md?metric=AUC>): Higher is better; unit: SCALAR.

- [AUPRC](<https://www.sota2.com/research/sota/hrd-prediction-on-tcga-luad.md?metric=AUPRC>): Higher is better; unit: SCALAR.

## Recorded results

| Method | AUC | Result date | Report paper |
| --- | --- | --- | --- |
| dwa + pcgrad | 0.734 | Not recorded | 68fa72771e209131cea56894 |
| dwa | 0.733 | Not recorded | 68fa72771e209131cea56894 |
| uncert | 0.732 | Not recorded | 68fa72771e209131cea56894 |
| cagrad | 0.726 | Not recorded | 68fa72771e209131cea56894 |
| dwa + graddrop | 0.726 | Not recorded | 68fa72771e209131cea56894 |
| uncert + graddrop | 0.726 | Not recorded | 68fa72771e209131cea56894 |
| uncert + cagrad | 0.724 | Not recorded | 68fa72771e209131cea56894 |
| autol | 0.722 | Not recorded | 68fa72771e209131cea56894 |
| pcgrad | 0.721 | Not recorded | 68fa72771e209131cea56894 |
| autol + pcgrad | 0.72 | Not recorded | 68fa72771e209131cea56894 |
| autol + cagrad | 0.719 | Not recorded | 68fa72771e209131cea56894 |
| dwa + cagrad | 0.718 | Not recorded | 68fa72771e209131cea56894 |
| uncert + pcgrad | 0.718 | Not recorded | 68fa72771e209131cea56894 |
| baseline | 0.716 | Not recorded | 68fa72771e209131cea56894 |
| graddrop | 0.711 | Not recorded | 68fa72771e209131cea56894 |
| autol + graddrop | 0.708 | Not recorded | 68fa72771e209131cea56894 |
| SOTA | 0.7 | Not recorded | 68fa72771e209131cea56894 |
| naive | 0.696 | Not recorded | 68fa72771e209131cea56894 |

### dwa + pcgrad

AUC: 0.734. Result ID: 69923ac73a6c3148490d791e.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa","gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction.

### dwa

AUC: 0.733. Result ID: 69923ac73a6c3148490d7917.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa"}. This record does not assert independent reproduction.

### uncert

AUC: 0.732. Result ID: 69923ac73a6c3148490d7918.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty"}. This record does not assert independent reproduction.

### cagrad

AUC: 0.726. Result ID: 69923ac73a6c3148490d791c.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"gradient\_strategy":"cagrad"}. This record does not assert independent reproduction.

### dwa + graddrop

AUC: 0.726. Result ID: 69923ac73a6c3148490d791d.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa","gradient\_strategy":"graddrop"}. This record does not assert independent reproduction.

### uncert + graddrop

AUC: 0.726. Result ID: 69923ac73a6c3148490d7920.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty","gradient\_strategy":"graddrop"}. This record does not assert independent reproduction.

### uncert + cagrad

AUC: 0.724. Result ID: 69923ac73a6c3148490d7922.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty","gradient\_strategy":"cagrad"}. This record does not assert independent reproduction.

### autol

AUC: 0.722. Result ID: 69923ac73a6c3148490d7919.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol"}. This record does not assert independent reproduction.

### pcgrad

AUC: 0.721. Result ID: 69923ac73a6c3148490d791b.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction.

### autol + pcgrad

AUC: 0.72. Result ID: 69923ac73a6c3148490d7924.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol","gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction.

### autol + cagrad

AUC: 0.719. Result ID: 69923ac73a6c3148490d7925.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol","gradient\_strategy":"cagrad"}. This record does not assert independent reproduction.

### dwa + cagrad

AUC: 0.718. Result ID: 69923ac73a6c3148490d791f.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa","gradient\_strategy":"cagrad"}. This record does not assert independent reproduction.

### uncert + pcgrad

AUC: 0.718. Result ID: 69923ac73a6c3148490d7921.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty","gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction.

### baseline

AUC: 0.716. Result ID: 69923ac73a6c3148490d7915.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":false}. This record does not assert independent reproduction.

### graddrop

AUC: 0.711. Result ID: 69923ac73a6c3148490d791a.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"gradient\_strategy":"graddrop"}. This record does not assert independent reproduction.

### autol + graddrop

AUC: 0.708. Result ID: 69923ac73a6c3148490d7923.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol","gradient\_strategy":"graddrop"}. This record does not assert independent reproduction.

### SOTA

AUC: 0.7. Result ID: 69923ac73a6c3148490d7914.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

### naive

AUC: 0.696. Result ID: 69923ac73a6c3148490d7916.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"naive"}. This record does not assert independent reproduction.

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