# HRD prediction on CPTAC-LUAD

Source: [HRD prediction on CPTAC-LUAD](<https://www.sota2.com/research/sota/hrd-prediction-on-cptac-luad>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2026-02-26T05:24:39.935Z

Evaluation of models predicting Homologous Recombination Deficiency (HRD) status using the CPTAC Lung Adenocarcinoma (LUAD) cohort, assessed using metrics like AUC and PRC.

A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage.

| Scope | Recorded value |
| --- | --- |
| Task | HRD prediction |
| Dataset (including any stated split) | CPTAC-LUAD |
| Metric | AUC |
| Unit | SCALAR |
| Direction | Higher is better |
| Results loaded | 18 of 18 |
| Coverage | All results currently returned for this benchmark |

Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol.

## Metrics

- [AUC](<https://www.sota2.com/research/sota/hrd-prediction-on-cptac-luad.md?metric=AUC>): Higher is better; unit: SCALAR.

- [PRC](<https://www.sota2.com/research/sota/hrd-prediction-on-cptac-luad.md?metric=PRC>): Higher is better; unit: SCALAR.

## Recorded results

| Method | AUC | Result date | Report paper |
| --- | --- | --- | --- |
| autol + cagrad | 0.861 | Not recorded | 68fa72771e209131cea56894 |
| autol + pcgrad | 0.856 | Not recorded | 68fa72771e209131cea56894 |
| dwa + cagrad | 0.855 | Not recorded | 68fa72771e209131cea56894 |
| cagrad | 0.854 | Not recorded | 68fa72771e209131cea56894 |
| autol | 0.852 | Not recorded | 68fa72771e209131cea56894 |
| autol + graddrop | 0.848 | Not recorded | 68fa72771e209131cea56894 |
| graddrop | 0.844 | Not recorded | 68fa72771e209131cea56894 |
| uncert + cagrad | 0.844 | Not recorded | 68fa72771e209131cea56894 |
| pcgrad | 0.841 | Not recorded | 68fa72771e209131cea56894 |
| uncert + graddrop | 0.839 | Not recorded | 68fa72771e209131cea56894 |
| dwa | 0.836 | Not recorded | 68fa72771e209131cea56894 |
| uncert + pcgrad | 0.836 | Not recorded | 68fa72771e209131cea56894 |
| dwa + graddrop | 0.833 | Not recorded | 68fa72771e209131cea56894 |
| uncert | 0.831 | Not recorded | 68fa72771e209131cea56894 |
| dwa + pcgrad | 0.83 | Not recorded | 68fa72771e209131cea56894 |
| SOTA | 0.82 | Not recorded | 68fa72771e209131cea56894 |
| naive | 0.812 | Not recorded | 68fa72771e209131cea56894 |
| baseline | 0.81 | Not recorded | 68fa72771e209131cea56894 |

### autol + cagrad

AUC: 0.861. Result ID: 69923ac73a6c3148490d7937.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol","gradient\_strategy":"cagrad"}. This record does not assert independent reproduction.

### autol + pcgrad

AUC: 0.856. Result ID: 69923ac73a6c3148490d7936.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol","gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction.

### dwa + cagrad

AUC: 0.855. Result ID: 69923ac73a6c3148490d7931.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa","gradient\_strategy":"cagrad"}. This record does not assert independent reproduction.

### cagrad

AUC: 0.854. Result ID: 69923ac73a6c3148490d792e.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"gradient\_strategy":"cagrad"}. This record does not assert independent reproduction.

### autol

AUC: 0.852. Result ID: 69923ac73a6c3148490d792b.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol"}. This record does not assert independent reproduction.

### autol + graddrop

AUC: 0.848. Result ID: 69923ac73a6c3148490d7935.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol","gradient\_strategy":"graddrop"}. This record does not assert independent reproduction.

### graddrop

AUC: 0.844. Result ID: 69923ac73a6c3148490d792c.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"gradient\_strategy":"graddrop"}. This record does not assert independent reproduction.

### uncert + cagrad

AUC: 0.844. Result ID: 69923ac73a6c3148490d7934.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty","gradient\_strategy":"cagrad"}. This record does not assert independent reproduction.

### pcgrad

AUC: 0.841. Result ID: 69923ac73a6c3148490d792d.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction.

### uncert + graddrop

AUC: 0.839. Result ID: 69923ac73a6c3148490d7932.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty","gradient\_strategy":"graddrop"}. This record does not assert independent reproduction.

### dwa

AUC: 0.836. Result ID: 69923ac73a6c3148490d7929.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa"}. This record does not assert independent reproduction.

### uncert + pcgrad

AUC: 0.836. Result ID: 69923ac73a6c3148490d7933.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty","gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction.

### dwa + graddrop

AUC: 0.833. Result ID: 69923ac73a6c3148490d792f.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa","gradient\_strategy":"graddrop"}. This record does not assert independent reproduction.

### uncert

AUC: 0.831. Result ID: 69923ac73a6c3148490d792a.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty"}. This record does not assert independent reproduction.

### dwa + pcgrad

AUC: 0.83. Result ID: 69923ac73a6c3148490d7930.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa","gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction.

### SOTA

AUC: 0.82. Result ID: 69923ac73a6c3148490d7926.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

### naive

AUC: 0.812. Result ID: 69923ac73a6c3148490d7928.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"naive"}. This record does not assert independent reproduction.

### baseline

AUC: 0.81. Result ID: 69923ac73a6c3148490d7927.

[Reporting paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa72771e209131cea56894.md>)

[Implementation](<https://github.com/Avic3nna/joint-mtl-cpath>)

Recorded evaluation configuration: {"multi\_task":false}. This record does not assert independent reproduction.

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