# Gene Regulatory Network Inference on Breast cancer in pseudotime

Source: [Gene Regulatory Network Inference on Breast cancer in pseudotime](<https://www.sota2.com/research/sota/gene-regulatory-network-inference-on-breast-cancer-in-pseudotime>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2026-02-26T06:04:31.629Z

Evaluation of models designed to infer gene regulatory networks using gene expression data derived from breast cancer studies analyzed via pseudotime ordering.

A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage.

| Scope | Recorded value |
| --- | --- |
| Task | Gene Regulatory Network Inference |
| Dataset (including any stated split) | Breast cancer in pseudotime |
| Metric | Sparsity |
| Unit | SCALAR |
| Direction | Higher is better |
| Results loaded | 12 of 12 |
| Coverage | All results currently returned for this benchmark |

Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol.

## Metrics

- [Sparsity](<https://www.sota2.com/research/sota/gene-regulatory-network-inference-on-breast-cancer-in-pseudotime.md?metric=Sparsity>): Higher is better; unit: SCALAR.

- [Balanced Acc](<https://www.sota2.com/research/sota/gene-regulatory-network-inference-on-breast-cancer-in-pseudotime.md?metric=Balanced%20Acc>): Higher is better; unit: PERCENT.

- [MSE](<https://www.sota2.com/research/sota/gene-regulatory-network-inference-on-breast-cancer-in-pseudotime.md?metric=MSE>): Lower is better; unit: SCALAR.

## Recorded results

| Method | Sparsity | Result date | Report paper |
| --- | --- | --- | --- |
| SparseFlow | 95.7 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |
| BioPrune | 93.44 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |
| DASH | 92.71 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |
| PINN + MP | 92 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |
| Iter. SynFlow | 91.93 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |
| DST | 67.02 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |
| IMP | 36.02 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |
| PathReg | 14.09 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |
| C-NODE | 11.2 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |
| L0 | 10.77 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |
| PINN | 0.11 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |
| Baseline | 0.03 | Not recorded | 68fa5f6e1e209131ce9e9cf7 |

### SparseFlow

Sparsity: 95.7. Result ID: 698bc6fd7a967eddb7714699.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa6b421e209131cea2d093.md>)

Recorded evaluation configuration: {"Prior information for sparsification":false}. This record does not assert independent reproduction.

### BioPrune

Sparsity: 93.44. Result ID: 698bc6fd7a967eddb771469a.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Implementation](<https://github.com/QuackenbushLab/DASH>)

Recorded evaluation configuration: {"Prior information for sparsification":true,"Suggested baseline":true}. This record does not assert independent reproduction.

### DASH

Sparsity: 92.71. Result ID: 698bc6fd7a967eddb771469b.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Implementation](<https://github.com/QuackenbushLab/DASH>)

Recorded evaluation configuration: {"Prior information for sparsification":true,"Suggested method":true,"Lambda values":"0.995, 0.95"}. This record does not assert independent reproduction.

### PINN + MP

Sparsity: 92. Result ID: 698bc6fd7a967eddb771469c.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Implementation](<https://github.com/QuackenbushLab/DASH>)

Recorded evaluation configuration: {"Prior information for sparsification":true,"Suggested baseline":true}. This record does not assert independent reproduction.

### Iter. SynFlow

Sparsity: 91.93. Result ID: 698bc6fd7a967eddb7714698.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa3d821e209131ce8e0b67.md>)

Recorded evaluation configuration: {"Prior information for sparsification":false}. This record does not assert independent reproduction.

### DST

Sparsity: 67.02. Result ID: 698bc6fd7a967eddb7714696.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa67881e209131cea16aff.md>)

Recorded evaluation configuration: {"Prior information for sparsification":false}. This record does not assert independent reproduction.

### IMP

Sparsity: 36.02. Result ID: 698bc6fd7a967eddb7714697.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa656f1e209131cea0a651.md>)

Recorded evaluation configuration: {"Prior information for sparsification":false}. This record does not assert independent reproduction.

### PathReg

Sparsity: 14.09. Result ID: 698bc6fd7a967eddb7714694.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa6dc21e209131cea3be2b.md>)

[Implementation](<https://github.com/theislab/PathReg>)

Recorded evaluation configuration: {"Prior information for sparsification":false}. This record does not assert independent reproduction.

### C-NODE

Sparsity: 11.2. Result ID: 698bc6fd7a967eddb7714693.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa76cc1e209131cea6f218.md>)

Recorded evaluation configuration: {"Prior information for sparsification":false}. This record does not assert independent reproduction.

### L0

Sparsity: 10.77. Result ID: 698bc6fd7a967eddb7714692.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa647d1e209131cea04d19.md>)

Recorded evaluation configuration: {"Prior information for sparsification":false}. This record does not assert independent reproduction.

### PINN

Sparsity: 0.11. Result ID: 698bc6fd7a967eddb7714695.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

Recorded evaluation configuration: {"Prior information for sparsification":true}. This record does not assert independent reproduction.

### Baseline

Sparsity: 0.03. Result ID: 698bc6fd7a967eddb7714691.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6e1e209131ce9e9cf7.md>)

Recorded evaluation configuration: {"Prior information for sparsification":false}. This record does not assert independent reproduction.

Page 1 of 1. This is an index page, not the full collection.
