# Few-shot Biomarker and Subtype Prediction on CPTAC k=25 (TCGA-trained, test)

Source: [Few-shot Biomarker and Subtype Prediction on CPTAC k=25 (TCGA-trained, test)](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2026-02-26T05:48:48.303Z

Evaluation of few-shot learning models for predicting specific cancer biomarkers and molecular subtypes using the CPTAC dataset, trained under k=25 few-shot conditions derived from TCGA features, evaluated on the test split.

A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage.

| Scope | Recorded value |
| --- | --- |
| Task | Few-shot Biomarker and Subtype Prediction |
| Dataset (including any stated split) | CPTAC TCGA-trained few-shot (k=25) (test) |
| Metric | Lung ST Score |
| Unit | PERCENT |
| Direction | Higher is better |
| Results loaded | 15 of 15 |
| Coverage | All results currently returned for this benchmark |

Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol.

## Metrics

- [Lung ST Score](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=Lung%20ST%20Score>): Higher is better; unit: PERCENT.

- [AUPRC](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=AUPRC>): Higher is better; unit: PERCENT.

- [LUAD STK11 Score](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=LUAD%20STK11%20Score>): Higher is better; unit: PERCENT.

- [LUAD EGFR Score](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=LUAD%20EGFR%20Score>): Higher is better; unit: PERCENT.

- [LUAD TP53 Score](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=LUAD%20TP53%20Score>): Higher is better; unit: PERCENT.

- [BRCA ESR1 Score](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=BRCA%20ESR1%20Score>): Higher is better; unit: PERCENT.

- [BRCA PGR Score](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=BRCA%20PGR%20Score>): Higher is better; unit: PERCENT.

- [BRCA ERBB2 Score](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=BRCA%20ERBB2%20Score>): Higher is better; unit: PERCENT.

- [COAD MSI Score](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=COAD%20MSI%20Score>): Higher is better; unit: PERCENT.

- [COAD BRAF Score](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=COAD%20BRAF%20Score>): Higher is better; unit: PERCENT.

- [Side Prediction Score](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=Side%20Prediction%20Score>): Higher is better; unit: PERCENT.

- [Average Prediction Score](<https://www.sota2.com/research/sota/few-shot-biomarker-and-subtype-prediction-on-cptac-k-25-tcga-trained-test.md?metric=Average%20Prediction%20Score>): Higher is better; unit: PERCENT.

## Recorded results

| Method | Lung ST Score | Result date | Report paper |
| --- | --- | --- | --- |
| PRISM | 98.3 | Not recorded | 68fa77981e209131cea743e8 |
| COBRA-H0 | 96 | Not recorded | 68fa77981e209131cea743e8 |
| COBRA-UNI | 95 | Not recorded | 68fa77981e209131cea743e8 |
| COBRA-V2 | 94.4 | Not recorded | 68fa77981e209131cea743e8 |
| MADELEINE | 94.1 | Not recorded | 68fa77981e209131cea743e8 |
| CONCH | 92 | Not recorded | 68fa77981e209131cea743e8 |
| COBRA-CTP | 90.2 | Not recorded | 68fa77981e209131cea743e8 |
| CHIEF | 85.2 | Not recorded | 68fa77981e209131cea743e8 |
| Virchow2 | 84.9 | Not recorded | 68fa77981e209131cea743e8 |
| GigaPath | 83.7 | Not recorded | 68fa77981e209131cea743e8 |
| H-Optimus | 83 | Not recorded | 68fa77981e209131cea743e8 |
| UNI | 81.1 | Not recorded | 68fa77981e209131cea743e8 |
| Virchow | 80.6 | Not recorded | 68fa77981e209131cea743e8 |
| GigaPath-SE | 80.1 | Not recorded | 68fa77981e209131cea743e8 |
| CTransPath | 72.9 | Not recorded | 68fa77981e209131cea743e8 |

### PRISM

Lung ST Score: 98.3. Result ID: 69954beb3badfaffe63b1dcf.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa73421e209131cea5b55b.md>)

Recorded evaluation configuration: {"k":25}. This record does not assert independent reproduction.

### COBRA-H0

Lung ST Score: 96. Result ID: 69954beb3badfaffe63b1dd1.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25,"Backbone":"H-Optimus-0","Feature\_Fusion":"All four training FMs used for weighting vector"}. This record does not assert independent reproduction.

### COBRA-UNI

Lung ST Score: 95. Result ID: 69954beb3badfaffe63b1dd0.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25,"Backbone":"UNI","Feature\_Fusion":"All four training FMs used for weighting vector"}. This record does not assert independent reproduction.

### COBRA-V2

Lung ST Score: 94.4. Result ID: 69954beb3badfaffe63b1dd2.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25,"Backbone":"Virchow-2","Feature\_Fusion":"All four training FMs used for weighting vector"}. This record does not assert independent reproduction.

### MADELEINE

Lung ST Score: 94.1. Result ID: 69954beb3badfaffe63b1dce.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa745e1e209131cea613b1.md>)

Recorded evaluation configuration: {"k":25}. This record does not assert independent reproduction.

### CONCH

Lung ST Score: 92. Result ID: 69954beb3badfaffe63b1dc7.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25,"Pooling":"Mean over patch embeddings"}. This record does not assert independent reproduction.

### COBRA-CTP

Lung ST Score: 90.2. Result ID: 69954beb3badfaffe63b1dcd.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25,"Backbone":"CTransPath","Feature\_Fusion":"All four training FMs used for weighting vector"}. This record does not assert independent reproduction.

### CHIEF

Lung ST Score: 85.2. Result ID: 69954beb3badfaffe63b1dcc.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25}. This record does not assert independent reproduction.

### Virchow2

Lung ST Score: 84.9. Result ID: 69954beb3badfaffe63b1dca.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa758d1e209131cea688d5.md>)

Recorded evaluation configuration: {"k":25,"Pooling":"Mean over patch embeddings"}. This record does not assert independent reproduction.

### GigaPath

Lung ST Score: 83.7. Result ID: 69954beb3badfaffe63b1dc8.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25,"Pooling":"Mean over patch embeddings"}. This record does not assert independent reproduction.

### H-Optimus

Lung ST Score: 83. Result ID: 69954beb3badfaffe63b1dc9.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25,"Pooling":"Mean over patch embeddings"}. This record does not assert independent reproduction.

### UNI

Lung ST Score: 81.1. Result ID: 69954beb3badfaffe63b1dc6.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25,"Pooling":"Mean over patch embeddings"}. This record does not assert independent reproduction.

### Virchow

Lung ST Score: 80.6. Result ID: 69954beb3badfaffe63b1dc4.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25,"Pooling":"Mean over patch embeddings"}. This record does not assert independent reproduction.

### GigaPath-SE

Lung ST Score: 80.1. Result ID: 69954beb3badfaffe63b1dcb.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25,"Module":"Slide Encoder"}. This record does not assert independent reproduction.

### CTransPath

Lung ST Score: 72.9. Result ID: 69954beb3badfaffe63b1dc5.

[Reporting paper](<https://www.sota2.com/research/paper/68fa77981e209131cea743e8.md>)

Recorded evaluation configuration: {"k":25,"Pooling":"Mean over patch embeddings"}. This record does not assert independent reproduction.

Page 1 of 1. This is an index page, not the full collection.
