# Antimicrobial Peptide Prediction on XUAMP Unified Benchmarking (test)

Source: [Antimicrobial Peptide Prediction on XUAMP Unified Benchmarking (test)](<https://www.sota2.com/research/sota/antimicrobial-peptide-prediction-on-xuamp-unified-benchmarking-test>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2026-02-26T05:25:45.507Z

Evaluation of model performance for Antimicrobial Peptide Prediction using the test split of the XUAMP Unified Benchmarking dataset, measured by AUROC and MCC.

A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage.

| Scope | Recorded value |
| --- | --- |
| Task | Antimicrobial Peptide Prediction |
| Dataset (including any stated split) | XUAMP Unified Benchmarking (test) |
| Metric | AUROC |
| Unit | SCALAR |
| Direction | Higher is better |
| Results loaded | 12 of 12 |
| Coverage | All results currently returned for this benchmark |

Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol.

## Metrics

- [AUROC](<https://www.sota2.com/research/sota/antimicrobial-peptide-prediction-on-xuamp-unified-benchmarking-test.md?metric=AUROC>): Higher is better; unit: SCALAR.

- [MCC](<https://www.sota2.com/research/sota/antimicrobial-peptide-prediction-on-xuamp-unified-benchmarking-test.md?metric=MCC>): Higher is better; unit: SCALAR.

## Recorded results

| Method | AUROC | Result date | Report paper |
| --- | --- | --- | --- |
| ECFP | 0.75 | Not recorded | 68fa5f851e209131ce9ea943 |
| RDKit | 0.745 | Not recorded | 68fa5f851e209131ce9ea943 |
| AMPfun | 0.735 | Not recorded | 68fa5f851e209131ce9ea943 |
| TT | 0.731 | Not recorded | 68fa5f851e209131ce9ea943 |
| AMPEP | 0.727 | Not recorded | 68fa5f851e209131ce9ea943 |
| AMPlify | 0.697 | Not recorded | 68fa5f851e209131ce9ea943 |
| ADAM-HMM | 0.684 | Not recorded | 68fa5f851e209131ce9ea943 |
| MLAMP | 0.629 | Not recorded | 68fa5f851e209131ce9ea943 |
| ampir | 0.619 | Not recorded | 68fa5f851e209131ce9ea943 |
| ADAM-SVM | 0.612 | Not recorded | 68fa5f851e209131ce9ea943 |
| iAMP-2L | 0.592 | Not recorded | 68fa5f851e209131ce9ea943 |
| AMPscanner V2 | 0.585 | Not recorded | 68fa5f851e209131ce9ea943 |

### ECFP

AUROC: 0.75. Result ID: 698bcaa47a967eddb771633e.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

[Implementation](<https://github.com/scikit-fingerprints/peptides_molecular_fingerprints_classification>)

Recorded evaluation configuration: {"classifier":"LightGBM"}. This record does not assert independent reproduction.

### RDKit

AUROC: 0.745. Result ID: 698bcaa47a967eddb771633c.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

[Implementation](<https://github.com/scikit-fingerprints/peptides_molecular_fingerprints_classification>)

Recorded evaluation configuration: {"classifier":"LightGBM"}. This record does not assert independent reproduction.

### AMPfun

AUROC: 0.735. Result ID: 698bcaa47a967eddb771633b.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

### TT

AUROC: 0.731. Result ID: 698bcaa47a967eddb771633d.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

[Implementation](<https://github.com/scikit-fingerprints/peptides_molecular_fingerprints_classification>)

Recorded evaluation configuration: {"classifier":"LightGBM"}. This record does not assert independent reproduction.

### AMPEP

AUROC: 0.727. Result ID: 698bcaa47a967eddb771633a.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

### AMPlify

AUROC: 0.697. Result ID: 698bcaa47a967eddb7716339.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

### ADAM-HMM

AUROC: 0.684. Result ID: 698bcaa47a967eddb7716338.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

### MLAMP

AUROC: 0.629. Result ID: 698bcaa47a967eddb7716337.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

### ampir

AUROC: 0.619. Result ID: 698bcaa47a967eddb7716336.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

### ADAM-SVM

AUROC: 0.612. Result ID: 698bcaa47a967eddb7716335.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

### iAMP-2L

AUROC: 0.592. Result ID: 698bcaa47a967eddb7716334.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

### AMPscanner V2

AUROC: 0.585. Result ID: 698bcaa47a967eddb7716333.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f851e209131ce9ea943.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

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