# Antibody paratope prediction on SAbDab (10-fold cross-validation)

Source: [Antibody paratope prediction on SAbDab (10-fold cross-validation)](<https://www.sota2.com/research/sota/antibody-paratope-prediction-on-sabdab-10-fold-cross-validation>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2026-02-26T06:00:19.735Z

Evaluation of antibody paratope prediction performance using the SAbDab dataset under a 10-fold cross-validation scheme, measured by ROC AUC and MCC.

A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage.

| Scope | Recorded value |
| --- | --- |
| Task | Antibody paratope prediction |
| Dataset (including any stated split) | SAbDab (10-fold cross-validation) |
| Metric | ROC AUC |
| Unit | PERCENT |
| Direction | Higher is better |
| Results loaded | 4 of 4 |
| Coverage | All results currently returned for this benchmark |

Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol.

## Metrics

- [ROC AUC](<https://www.sota2.com/research/sota/antibody-paratope-prediction-on-sabdab-10-fold-cross-validation.md?metric=ROC%20AUC>): Higher is better; unit: PERCENT.

- [MCC](<https://www.sota2.com/research/sota/antibody-paratope-prediction-on-sabdab-10-fold-cross-validation.md?metric=MCC>): Higher is better; unit: SCALAR.

## Recorded results

| Method | ROC AUC | Result date | Report paper |
| --- | --- | --- | --- |
| AG-Fast-Parapred | 89.9 | Not recorded | 68fa5f011e209131ce9e6dcd |
| Fast-Parapred | 88.3 | Not recorded | 68fa5f011e209131ce9e6dcd |
| Parapred | 88 | Not recorded | 68fa5f011e209131ce9e6dcd |
| proABC | 85.1 | Not recorded | 68fa5f011e209131ce9e6dcd |

### AG-Fast-Parapred

ROC AUC: 89.9. Result ID: 698bbb2d7a967eddb770ee4c.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f011e209131ce9e6dcd.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f011e209131ce9e6dcd.md>)

Recorded evaluation configuration: {"Epoch time":"0.178 ± 0.020s"}. This record does not assert independent reproduction.

### Fast-Parapred

ROC AUC: 88.3. Result ID: 698bbb2d7a967eddb770ee4b.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f011e209131ce9e6dcd.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f011e209131ce9e6dcd.md>)

Recorded evaluation configuration: {"Epoch time":"0.085 ± 0.015s"}. This record does not assert independent reproduction.

### Parapred

ROC AUC: 88. Result ID: 698bbb2d7a967eddb770ee4a.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f011e209131ce9e6dcd.md>)

Recorded evaluation configuration: {"Epoch time":"0.190 ± 0.019s"}. This record does not assert independent reproduction.

### proABC

ROC AUC: 85.1. Result ID: 698bbb2d7a967eddb770ee49.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f011e209131ce9e6dcd.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

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