# Annotation by Clicks: A Point-Supervised Contrastive Variance Method for Medical Semantic Segmentation Source: [Annotation by Clicks: A Point-Supervised Contrastive Variance Method for Medical Semantic Segmentation]() Collection index: [llms.txt]() Data updated: 2025-10-27T06:19:28.634Z Authors: Qing En, Yuhong Guo Published: 2022-12-17T01:07:21.000Z ## Abstract Medical image segmentation methods typically rely on numerous dense annotated images for model training, which are notoriously expensive and time-consuming to collect. To alleviate this burden, weakly supervised techniques have been exploited to train segmentation models with less expensive annotations. In this paper, we propose a novel point-supervised contrastive variance method (PSCV) for medical image semantic segmentation, which only requires one pixel-point from each organ category to be annotated. The proposed method trains the base segmentation network by using a novel contrastive variance (CV) loss to exploit the unlabeled pixels and a partial cross-entropy loss on the labeled pixels. The CV loss function is designed to exploit the statistical spatial distribution properties of organs in medical images and their variance distribution map representations to enforce discriminative predictions over the unlabeled pixels. Experimental results on two standard medical image datasets demonstrate that the proposed method outperforms the state-of-the-art weakly supervised methods on point-supervised medical image semantic segmentation tasks. ## Recorded benchmark results A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage. ## Original sources and implementation [Original paper]() [PDF]()