# Joint Prediction of Meningioma Grade and Brain Invasion via Task-Aware Contrastive Learning Source: [Joint Prediction of Meningioma Grade and Brain Invasion via Task-Aware Contrastive Learning]() Collection index: [llms.txt]() Data updated: 2026-01-01T15:00:22.288Z Authors: Tianling Liu, Wennan Liu, Lequan Yu, Liang Wan, Tong Han, Lei Zhu Published: 2022-09-04T02:50:47.000Z ## Abstract Preoperative and noninvasive prediction of the meningioma grade is important in clinical practice, as it directly influences the clinical decision making. What's more, brain invasion in meningioma (i.e., the presence of tumor tissue within the adjacent brain tissue) is an independent criterion for the grading of meningioma and influences the treatment strategy. Although efforts have been reported to address these two tasks, most of them rely on hand-crafted features and there is no attempt to exploit the two prediction tasks simultaneously. In this paper, we propose a novel task-aware contrastive learning algorithm to jointly predict meningioma grade and brain invasion from multi-modal MRIs. Based on the basic multi-task learning framework, our key idea is to adopt contrastive learning strategy to disentangle the image features into task-specific features and task-common features, and explicitly leverage their inherent connections to improve feature representation for the two prediction tasks. In this retrospective study, an MRI dataset was collected, for which 800 patients (containing 148 high-grade, 62 invasion) were diagnosed with meningioma by pathological analysis. Experimental results show that the proposed algorithm outperforms alternative multi-task learning methods, achieving AUCs of 0:8870 and 0:9787 for the prediction of meningioma grade and brain invasion, respectively. The code is available at https://github.com/IsDling/predictTCL. ## Recorded benchmark results A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage. - [Meningioma grade prediction on Collected Meningioma MRI dataset (test)](): Meningioma grade prediction; Collected Meningioma MRI dataset (test); Sensitivity: 68.78. - [Brain invasion identification on Collected Meningioma MRI dataset (test)](): Brain invasion identification; Collected Meningioma MRI dataset (test); Sensitivity: 75.93. ## Original sources and implementation [Original paper]() [PDF]() [Implementation]()