# Emergence and Maintenance of Excitability: Kinetics over Structure

Source: [Emergence and Maintenance of Excitability: Kinetics over Structure](<https://www.sota2.com/research/paper/68fa5ece1e209131ce9e551a>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2025-10-28T13:56:20.149Z

Authors: Shimon Marom

Published: 2016-03-07T08:11:19.000Z

## Abstract

Emergence and maintenance of excitability is often phrased in terms of arriving at and remaining about a manifold of 'solutions' embedded in a high dimensional parameter space. Alongside studies that extend traditional focus on control-based regulation of structural parameters (channel densities), there is a budding interest in self-organization of kinetic parameters. In this picture, ionic channels are continually forced by activity in-and-out of a large pool of states not available for the mechanism of excitability. The process, acting on expressed structure, provides a bed for generation of a spectrum of excitability modes. Driven by microscopic fluctuations over a broad range of temporal scales, self-organization of kinetic parameters extends the metaphors and tools used in the study of development of excitability.

## Recorded benchmark results

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## Original sources and implementation

[Original paper](<https://arxiv.org/abs/1603.01970>)

[PDF](<https://arxiv.org/pdf/1603.01970.pdf>)