# Thermal Impact on Spiking Properties in Hodgkin-Huxley Neuron with Synaptic Stimulus

Source: [Thermal Impact on Spiking Properties in Hodgkin-Huxley Neuron with Synaptic Stimulus](<https://www.sota2.com/research/paper/68fa5e9a1e209131ce9e3c27>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2025-10-25T18:53:48.285Z

Authors: Shenbing Kuang, Jiafu Wang, Ting Zeng, Aiyin Cao

Published: 2007-03-07T09:24:59.000Z

## Abstract

The effect of environmental temperature on neuronal spiking behaviors is investigated by numerically simulating the temperature dependence of spiking threshold of the Hodgkin-Huxley neuron subject to synaptic stimulus. We find that the spiking threshold exhibits a global minimum in a "comfortable temperature" range where spike initiation needs weakest synaptic strength, indicating the occurrence of optimal use of synaptic transmission in neural system. We further explore the biophysical origin of this phenomenon in ion channel gating kinetics and also discuss its possible biological relevance in information processing in neural systems.

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## Original sources and implementation

[Original paper](<https://arxiv.org/abs/q-bio/0703017>)

[PDF](<https://arxiv.org/pdf/q-bio/0703017.pdf>)