# Nanosecond kinetics of phase separation in binary fluid studied by a combination of Laser-induced temperature jump and Forster Resonant Excitation Transfer probing

Source: [Nanosecond kinetics of phase separation in binary fluid studied by a combination of Laser-induced temperature jump and Forster Resonant Excitation Transfer probing](<https://www.sota2.com/research/paper/68fa45c71e209131ce91b4f6>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2025-10-25T05:27:52.841Z

Authors: Alexei Goun

Published: 2023-11-23T03:57:47.000Z

## Abstract

A novel technique for studying the demixing of binary fluids with nanosecond time resolution at nanometer spatial resolution is demonstrated. Nanosecond kinetics of phase separation initial stages in the water/2,6-lutidine mixture studied through the combination of a laser-induced temperature jump, and Forster Resonant Excitation Transfer techniques. A pair of chromophores: 8-hydroxy-1,3,6-pyrenetrisulfonate (HPTS) and Coumarin 480 form a FRET pair in the uniform phase of the mixture and separate into the components of the mixture in the nonuniform phase. The temperature jump that brings the mixture into a nonuniform phase is performed by the mid-infrared laser pulse. The exponential growth stage of phase separation is in the 5 to 20 nanoseconds range. The demonstrated technique can be applied to a broad range of chemical and biological systems.

## Recorded benchmark results

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## Original sources and implementation

[Original paper](<https://arxiv.org/abs/2311.13796>)

[PDF](<https://arxiv.org/pdf/2311.13796.pdf>)