# Chromatographic motion of substances involved in sequential first-order reactions

Source: [Chromatographic motion of substances involved in sequential first-order reactions](<https://www.sota2.com/research/paper/68fa3f521e209131ce8ec6ed>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2025-10-27T04:09:14.353Z

Authors: S. V. Ermolaev, A. K. Skasyrskaya

Published: 2021-04-21T14:31:29.000Z

## Abstract

Kinetics of sequential first-order reactions occurring in a chromatographic medium is developed. A model for motion of substances of a chain 1 -\> 2 -\> 3 -\> in an infinite chromatographic column is worked out, and a mathematical procedure and graphical method for obtaining the substance concentration as a function of reaction time and position in the column is proposed. Influence of different factors of chromatographic separation on formation of substance concentration profile is considered. Practical implementation of developed approach is demonstrated by the example of radioactive chain Ac-225 -\> Fr-221 -\> Bi-213 -\> used for modelling a radionuclidic Ac-225/Bi-213 generator producing Bi-213 via continuous separation and decay of intermediate Fr-221.

## Recorded benchmark results

A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage.

## Original sources and implementation

[Original paper](<https://arxiv.org/abs/2106.13599>)

[PDF](<https://arxiv.org/pdf/2106.13599.pdf>)