# Model for probing membrane-cortex adhesion by micropipette aspiration and fluctuation spectroscopy

Source: [Model for probing membrane-cortex adhesion by micropipette aspiration and fluctuation spectroscopy](<https://www.sota2.com/research/paper/68fa32fe1e209131ce88c61c>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2025-10-24T19:48:24.834Z

Authors: Ricard Alert, Jaume Casademunt, Jan Brugu\\'es, Pierre Sens

Published: 2016-02-09T15:13:08.000Z

## Abstract

We propose a model for membrane-cortex adhesion which couples membrane deformations, hydrodynamics and kinetics of membrane-cortex ligands. In its simplest form, the model gives explicit predictions for the critical pressure for membrane detachment and for the value of adhesion energy. We show that these quantities exhibit a significant dependence on the active acto-myosin stresses. The model provides a simple framework to access quantitative information on cortical activity by means of micropipette experiments. We also extend the model to incorporate fluctuations and show that detailed information on the stability of membrane-cortex coupling can be obtained by a combination of micropipette aspiration and fluctuation spectroscopy measurements.

## Recorded benchmark results

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## Original sources and implementation

[Original paper](<https://arxiv.org/abs/1602.03023>)

[PDF](<https://arxiv.org/pdf/1602.03023.pdf>)