# Exact Solution of the Munoz-Eaton Model for Protein Folding

Source: [Exact Solution of the Munoz-Eaton Model for Protein Folding](<https://www.sota2.com/research/paper/68fa25ba2c2a3760193b3391>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2025-10-24T10:55:29.056Z

Authors: Pierpaolo Bruscolini, Alessandro Pelizzola

Published: 2002-05-30T15:20:55.000Z

## Abstract

A transfer-matrix formalism is introduced to evaluate exactly the partition function of the Munoz-Eaton model, relating the folding kinetics of proteins of known structure to their thermodynamics and topology. This technique can be used for a generic protein, for any choice of the energy and entropy parameters, and in principle allows the model to be used as a first tool to characterize the dynamics of a protein of known native state and equilibrium population. Applications to a $\\beta$-hairpin and to protein CI-2, with comparisons to previous results, are also shown.

## Recorded benchmark results

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## Original sources and implementation

[Original paper](<https://arxiv.org/abs/cond-mat/0205646>)

[PDF](<https://arxiv.org/pdf/cond-mat/0205646.pdf>)