# Optothermal Molecule Trap

Source: [Optothermal Molecule Trap](<https://www.sota2.com/research/paper/68fa20717a2b558e293310b3>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2025-10-23T21:59:17.965Z

Authors: Stefan Duhr, Dieter Braun

Published: 2006-06-14T11:58:11.000Z

## Abstract

Thermophoresis moves molecules along temperature gradients, typically from hot to cold. We superpose fluid flow with thermophoretic molecule flow under well defined microfluidic conditions, imaged by fluorescence microscopy. DNA is trapped and accumulated 16-fold in regions where both flows move in opposite directions. Strong 800-fold accumulation is expected, however with slow trapping kinetics. The experiment is equally described by a three-dimensional and one-dimensional analytical model. As an application, we show how a radially converging temperature field confines short DNA into a 10 um small spot.

## Recorded benchmark results

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## Original sources and implementation

[Original paper](<https://arxiv.org/abs/physics/0606121>)

[PDF](<https://arxiv.org/pdf/physics/0606121.pdf>)