# On the origin of the deviation from the first order kinetics in inactivation of microbial cells by pulsed electric fields

Source: [On the origin of the deviation from the first order kinetics in inactivation of microbial cells by pulsed electric fields](<https://www.sota2.com/research/paper/68fa1fc87a2b558e2932c313>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2025-10-23T19:39:46.431Z

Authors: N. I. Lebovka, E. Vorobiev

Published: 2003-06-14T09:14:51.000Z

## Abstract

A computer model was developed for estimation of the kinetics of microbial inactivation by pulsed electric field. The model is based on the electroporation theory of individual membrane damage, where spherical cell geometry and distribution of cell sizes are assumed. The variation of microbial cell sizes was assumed to follow a statistical probability distribution of the Gaussian type. Surviving kinetics was approximated by Weibull equation. The dependencies of two Weibull parameters (shape \\textit{n} and time $\\tau $, respectively) versus electric field intensity E and width of cell diameters distribution was studied.

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## Original sources and implementation

[Original paper](<https://arxiv.org/abs/physics/0306118>)

[PDF](<https://arxiv.org/pdf/physics/0306118.pdf>)